Resumen

The significant drop in sequencing costs boosted by chemistries optimization and sample multiplexation has resulted in an immense growth within the field of next-generation sequencing (NGS) in the last decade. This has allowed a diversification of techniques, promoting a rapid advance in knowledge on the molecular basis of human disease. Due to the applicability and importance of this technology in basic research, it has quickly migrated to the clinical setting. NGS enables clinicians to make improved diagnostic and treatment decisions, which ultimately may influence precision medicine.

Palabras clave: Next-generation sequencing clinical diagnostics clinical genomics.

2018-08-27   |   499 visitas   |   Evalua este artículo 0 valoraciones

Vol. 70 Núm.4. Julio-Agosto 2018 Pags. 153-157 Rev Invest Clin 2018; 70(4)