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Sábado 08 de agosto 2020   BUSQUEDA
Jiménez Castillo Gilberto A, Velázquez Álvarez Lorena, Mimenza Alvarado Alberto J., Juárez Arellano Sandra, Flores González Ángel, García Juárez Ignacio, Ávila Funes José Alberto, Aguilar  Navarro Sara G.
Long-term cognitive impairment after liver transplantation in a third-level hospital in Mexico City
J Lat Am Geriatric Med 2019; 5(2)  : 39-43


Objective: This study aims to study the frequency of cognitive impairment and neurocognitive pattern of post-transplanted liver patients after 1 year of intervention.

Materials and methods: This was a descriptive, cross-sectional study. It included transplant consult patients between October 2018 and May 2019. The cognitive evaluation included Montreal cognitive assessment (MoCA), 5-word test, and frontal assessment battery. ANOVA and Student’s t-test were performed.

Results: Seventy-six patients were included in the study. The mean age was 53.53 years (± 11.3). Forty-three (56.6%) of the patients had subjective memory loss, while only 33 (43.4%) had objective decline by cognitive tests. A frontal-subcortical pattern was shown. The affected domains were visuospatial abilities (-1.3 ± 0.95, p = 0.00), attention (-0.75 ± 1.2, p = 0.00), language (?0.99 ± 0.1.0, p = 0.00), abstraction (-0.61 ± 1.6, p = 0.015), and retrieval (-0.80 ± 1.1, p = 0.00).

Conclusions: Cognitive evaluation measured by MoCA is useful to detect cognitive impairment and a frontal-subcortical pattern in post-transplanted liver patients.

Palabras clave: Liver transplant, cognition, cognitive impairment
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