Resumen

Introduction: We aimed to evaluate the prevalence of "anti-HBc alone" among Syrian blood donors, highlighting the possibility of representing occult HBV infection. Methodology: Sera of 3,896 healthy blood donors were tested for both HBsAg and anti-HBc. HBsAg-negative, anti-HBc-positive samples were further tested for the antibodies to HBsAg (anti-HBs), and "anti-HBc alone" sera were tested for HBV DNA. Results: Of 3,830 HBsAg-negative donors, 63 were "anti-HBc alone" donors, five of whom were HBV DNA positive. Conclusions: Greater consideration should be given to the "anti-HBc alone" serological profile in blood screening, premarital testing, organ transplantation tests, and other HBV transmission-related procedures in Syria.

Palabras clave: Anti-HBc; anti-HBc alone; occult HBV infection; blood donors; Syria.

2014-09-01   |   324 visitas   |   Evalua este artículo 0 valoraciones

Vol. 8 Núm.8. Agosto 2014 Pags. 1013-1015 J Infect Developing Countries 2014; 8(8)