Hepatology highlights

Autor: Méndez Sánchez Nahum


Unzueta A, et al. Hepatitis E virus serum antibodies and RNA prevalence in patients evaluated for heart and kidney transplantation Unzueta A, et al. In the present study authors evaluated serum from heart and kidney transplant candidates. They found 11.4% (15/132) prevalence of anti-HEV IgG for heart transplant and 8.5% (17/201) for kidney transplant candidates, with an overall seroprevalence of 9.6% (32/333). None of the patients tested positive for HEV RNA in the serum. On multivariable analysis, age older than 60 years was associated with HEV infection (adjusted odds ratio, 3.34; 95% CI, 1.54-7.24; P = 0.002). Authors concluded that there was no evidence of acute HEV infection in those pre-transplant population and that older age seems to be associated with positive anti-HEV IgG. The results of this study are very interesting because few studies have evaluated pre-transplant seroprevalence of HEV infection. In addition this infection appears to be an emerging disease in the setting of donors to recipients of allografts. In fact, several previous case reports suggested that HEV transmission by blood products is possible

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2016-06-23   |   44 visitas   |   Evalua este artículo 0 valoraciones

Vol. 15 Núm.1. Enero-Febrero 2016 Pags. 4-5 Ann Hepatol 2016; 15(1)