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Pawar SV, et al. Most overweight and obese Indian children have nonalcoholic fatty liver disease Pawar SV, et al. The authors from Mumbai in India evaluated in their careful prospective school based cross sectional study a group of children in the age group from 11 to 15 years, measured their height and weight, and calculated the respective BMI. As expected, a liver biopsy as a gold standard to establish the diagnosis of NAFLD was not warranted, especially under the aspect of a clinical study and the risk of such invasive diagnostic procedure. Instead, the diagnosis of NAFLD was made by investigations used in daily clinical practice. These included elevated ALT, ultrasonography with the presence of at least two of three abnormal findings (diffusely increased liver echogenicity, vascular blurring, and deep attenuation of the ultrasound signal), and Fibroscan to measure stiffness in the right lobe of the liver. The diagnosis of NAFLD did not differentiate early and late stages but included steatosis, steatohepatitis, and significant fibrosis. Among the 616 children screened for overweight and obesity, 198 (32.1%) were overweight and obese.

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2016-11-17   |   392 visitas   |   Evalua este artículo 0 valoraciones

Vol. 15 Núm.6. Noviembre-Diciembre 2016 Pags. 812-814 Ann Hepatol 2016; 15(6)