Primary hyperaldosteronism, associated metabolic comorbidities and cardiovascular risk

Autores: Ruilova González Lizbet, Almeda Valdes Paloma, Janka Zires Marcela, Gómez Pérez Francisco Javier

Resumen

Background: Primary aldosteronism is the most common cause of secondary hypertension. There is little information about this disease in the Mexican population. The objective of this study is to evaluate patients with primary aldosteronism at a reference center and to describe its association with metabolic comorbidities and cardiovascular risk. Methods: Retrospective study of patients with primary aldosteronism treated from January 1987 to May 2014. Results: Thirty-seven patients with primary aldosteronism were included. The most common presentation was hypertension with hypokalemia (29.7%). The most frequent etiology was an adenoma (54%). Seventy-six percent underwent a unilateral adrenalectomy. Hypertension was cured in 48% of cases and in 40% there was an improvement. The use of antihypertensive medications after surgery decreased significantly (p = 0.009). 27% had metabolic syndrome. The median estimated 10-year cardiovascular risk was 5.2%. Conclusions: In our series the most frequent cause of primary aldosteronism was adenomas. Twenty-seven percent of the population had metabolic syndrome.

Palabras clave: Cardiovascular risk metabolic síndrome primary aldosteronism secondary hypertension.

2017-05-23   |   198 visitas   |   Evalua este artículo 0 valoraciones

Vol. 3 Núm.3. Julio-Septiembre 2016 Pags. 116-123 Rev Mex Endocrinol Metabol Nut 2016; 3(3)