Resumen

Article commented Rojas A, Gallego P, Gil-Gómez A, Muñoz-Hernández R, Rojas L, Maldonado R, Gallego R, et al. Natural extracts abolished lipid accumulation in cells harbouring non favourable PNPLA3 genotype. Ann Hepatol 2018. Non-alcoholic fatty liver disease (NAFLD) is a spectrum of conditions ranging from simple liver fat accumulation to inflammation and fibrosis, and ultimately to cirrhosis and liver cancer. NAFLD prevalence is increasing worldwide and it is expected to be the main reason for liver transplantation in the next decade. Although NAFLD in its early stages can be resolved by dietary modifications and lifestyle changes (weight loss), liver transplantation is the only existing treatment for the later stages of the disease. There is no drug approved as a specific treatment against NAFLD although vitamin E has shown to reduce NAFLD with a modest effect. Based on antioxidant effects, natural compounds including resveratrol, quercetin and anthocyanin have been proposed as treatment against NAFLD.

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2018-08-20   |   102 visitas   |   Evalua este artículo 0 valoraciones

Vol. 17 Núm.2. Marzo-Abril 2018 Pags. 180-181 Ann Hepatol 2018; 17(2)