Resumen

Introduction and aim. To investigate the association of adolescent obesity with nonalcoholic fatty liver disease (NAFLD) and related risk factors in Xi 'an, China. Material and methods. A total of 4141 adolescents (2,061 girls and 2,080 boys, mean age: 18.62+ 0.66 years, age range 15-22 years) were enrolled in this investigation. Anthropometric index was measured, and liver ultrasonography and liver function biochemical test were performed in all the subjects. T test, X² test and logistic regression analysis were used for statistical analyses. Results. The total rates of obesity was 7.9% (08/4,141). The prevalence rate of NAFLD was 8.1% (335/4141) with a declining trend from obesity, overweight to normal BMI. NAFLD prevalence rate in obese boys was significantly higher than in girls (X² = 56.5, P < 0.01). BMI, body weight, ALT, and AST in NAFLD group were higher than in non-NAFLD group (P < 0.05). The tangent point of ALT was 36 U/L using Youden index in boys, and 33 U/L in girls. Conclusion. The prevalence of obesity and NAFLD in adolescents is higher in Xi'an than anticipated. Body weight and BMI may be the associated independent risk factors of NAFLD.

Palabras clave: Adolescents obesity nonalcoholic fatty liver disease prevalence risk factors.

2018-08-22   |   99 visitas   |   Evalua este artículo 0 valoraciones

Vol. 17 Núm.1. Enero-Febrero 2018 Pags. 85-91 Ann Hepatol 2018; 17(1)