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TO THE EDITOR: In Budd Chiari Syndrome (BCS), a rare cause of hepatic failure, hepatic outflow is impaired through thrombosis or stenosis. Decreased sinusoidal blood flow and centrilobular ischemia results in subsequent tissue necrosis. Later, fibrotic remodelling occurs predominantly in the centrilobular area, leading to portal hypertension with eventually the development of ascites and esophageal varices. Here, we report the case of a 56-year-old female patient who was referred to our hospital for acute hepatic failure of unknown origin. On admission, typical clinical signs of a BCS such as jaundice, ascites and peripheral edema were present for 5 weeks. The patient reported an episode of abdominal discomfort eight months prior to admission to our hospital. The arterial phase of a CT scan of the abdomen at this time had shown a patchy appearance of the liver, the portal-venous phase was without pathological findings. Being self-limited, the complaints and the findings from the CT scan were not pursued further. The past medical history revealed no additional diseases and the patient did not take any medication. She did not consume any alcohol but smoked cigarettes for 30 years.

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2009-12-04   |   1,531 visitas   |   Evalua este artículo 0 valoraciones

Vol. 8 Núm.4. Octubre-Diciembre 2009 Pags. 388-389 Ann Hepatol 2009; 8(4)