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Dear Editor. A 51-year-old male firefighter with a remote history of deep vein thrombosis following ankle fracture was hospitalized at our center for a 2 week history of jaundice, ascites and right upper quadrant abdominal pain. His bloodwork on admission was significant for ALT and AST 100 times the upper limit of normal, bilirubin 30 mg/dL (normal 3-22), hemoglobin 16.8 mg/dL (normal 13.5-16), platelets 570 x 10⁹) cells/mL (normal 150-400 x 10⁹) and INR 1.5 (normal 0.9-1.1). CT scan revealed caudate lobe hypertrophy, compression of the inferior vena cava (ICV) and opacification of the hepatic veins, consistent with a diagnosis of Budd Chiari Syndrome (BCS). Further work-up revealed Janus kinase 2 mutation, confirming polycythemia ruba vera.

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2010-10-27   |   767 visitas   |   Evalua este artículo 0 valoraciones

Vol. 9 Núm.4. Octubre-Diciembre 2010 Pags. 473-474 Ann Hepatol 2010; 9(4)