Resumen

Hepatitis B virus (HBV) surface antigen (HBsAg) to anti-HBsAg (anti-HBs) antibody seroconversion is the best, final objective for all available chronic hepatitis B (CHB) treatments. Unfortunately, this goal is rarely obtained with the currently utilized therapeutic approaches. Here we describe the case of a CHB patient who was very successfully treated with a particular therapeutic schedule. The patient was initially treated with Lamivudine for four years. Subsequently, pegylated interferon alpha-2a was introduced for a period of one year. During this period of combined therapies, the patient showed a flare of aminotransferase values followed by complete normalization of liver biochemistry parameters and HBsAg/anti-HBs seroconversion that persisted up to 24 months after all therapies had been stopped.

Palabras clave: Chronic Hepatitis HBV Peg-IFN lamivudine.

2011-02-11   |   482 visitas   |   Evalua este artículo 0 valoraciones

Vol. 10 Núm.1. Enero-Marzo 2011 Pags. 84-87 Ann Hepatol 2011; 10(1)