The metabolic syndrome affects more than a third of the US and Mexican populations, predisposing to the development of some metabolic disorders. In fact, it is well recognized that subjects with generalized obesity suffer from a high risk of insulin resistance and its metabolic complications, such as type 2 diabetes mellitus, hypertriglyceridemia, low levels of high density lipoprotein cholesterol, hypertension, hepatic steatosis, hyperuricemia, and atherosclerotic vascular disease. Insulin resistance has long been considered to have a central role in the development of a range of metabolic disorders. Some of the links between components of the metabolic syndrome relate to insulin resistance, although about 30% of patients with the metabolic syndrome have normal insulin sensitivity. Insulin resistance is characterized by high plasma insulin concentration that fails to suppress plasma glucose normally.
2011-03-30 | 502 visitas | Evalua este artículo 0 valoraciones
Vol. 10 Núm.2. Abril-Junio 2011 Pags. 216-217 Ann Hepatol 2011; 10(2)