Abstracts

Rheumatoid arthritis 
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1. CARDIOVASCULAR DISEASE IN RHEUMATOID ARTHRITIS. NEW EVIDENCE IN A NEW COHORT JS Espinosa-Serna1, JC Amaya1, A Rodríguez-Rodríguez1, R Calderón1, J González-Gil1, O Calixto1, AC Céspedes1, RA Cifuentes1, A Iglesias-Gamarra1, AM Domínguez1, RD Mantilla1, JM Anaya1, A Rojas-Villarraga1 1CREA, Universidad del Rosario, Bogotá, Colombia. Introduction: Since patients with rheumatoid arthritis (RA) are characterized by a high incidence and mortality from cardiovascular disease (CVD), the present study evaluated the prevalence and associated factors in a new cohort. Methods: Analytical study of cross sectional in patients treated between 2006-2011. CVD was dichotomized according to presence or absence [high blood pressure, myocardial infarction (AMI), stroke and thrombosis]. The sociodemographic and clinical variables were collected through structured interview and review of medical record. A bivariate analysis and calculation of odds ratios (OR) was performed. Results: We included 603 patients (ACR 87), 491 (81.4%) women. CVD was recorded in 185 (31%): 154 hypertensive, 8 strokes, 18 AMI and 24 thrombosis. There were significant associations with dyslipidemia (OR 3.76, 95% CI: 2.48-5.72), BMI (OR 2.84, 95% CI: 1.40-5.73), diabetes (OR 3.28, 95% CI: 1.35-7.93), poliautoimmunity (OR 1.79, 95% CI 1.05-3.04), use of prednisolone (OR 1.62, 95% CI: 1.04-2.52) and hydroxychloroquine (OR 0.55, 95% CI 0.34 to 0.88). Conclusions: The present study confirms the high prevalence of CVD in RA, its association with traditional and nontraditional factors, highlighting the influence of poliautoimmunity as well as the adverse effect of prednisolone and protector effect of antimalarials.

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2012-01-12   |   513 visitas   |   Evalua este artículo 0 valoraciones

Vol. 18 Núm.5. Agosto 2011 Pags. 56-83 Rev. Colomb. Reumatol. 2011; 18(Supl. 1)