Hepatitis B viral load and risk of HBV-related liver disease:

from East to West? 

Autores: Harkisoen Soeradj, Arends Joop E, van Erpecum Karel J, van den Hoek Anneke, Hoepelman Andy IM


Chronic hepatitis B has a variable course in disease activity with a risk of clinical complications like liver cirrhosis and hepatocellular carcinoma. As clinical symptoms present in a late stage of the disease, identification of risk factors is important for early detection and therefore improvement of prognosis. Recently, two REVEAL-HBV studies from Taiwan have shown a positive correlation between viral load at any point in time and the development of cirrhosis and hepatocellular carcinoma. Due to differences in viral and host factors between Asians and other populations, it is unclear whether these results can be extrapolated to different populations. This manuscript will discuss viral predictors of hepatitis B related liver disease in relation to ethnic origin.

Palabras clave: Cirrhosis hepatitis B virus hepatocellular carcinoma viral load.

2012-02-10   |   422 visitas   |   Evalua este artículo 0 valoraciones

Vol. 11 Núm.2. Marzo-Abril 2012 Pags. 164-171 Ann Hepatol 2012; 11(2)