Atherosclerosis and chronic hepatitis C

Autores: Carrillo Córdova Luis Daniel, Uribe Esquivel Misael, Méndez Sánchez Nahum


Comments After the first report of an association of viral infection and atherosclerosis in 1970, several studies have suggested that there is a link between arteriosclerotic disease and persistent infection or seropositivity of certain micro-organisms, such as Chlamydia pneumoniae, cytomegalovirus, Helicobacter pylori, and herpes simplex virus. The pathogenetic mechanisms may vary and are still poorly understood. Evidence demonstrate that hepatitis C virus, alone or in association with other viral infections, is involved in the development and progression of carotid atherosclerosis. Given their association with inflammation which is now seen as a key event in the atherosclerotic process. Infectious pathogens induce macrophage foam cell formation and induce activation of the immune response and potentiate the immune inflammatory reaction underlying atherosclerosis. A retrospective analysis undertook a systematic review of the literature to study the association between HCV and carotid atherosclerotic plaques. A total of 18 studies in the English language were identified.

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2012-06-14   |   595 visitas   |   Evalua este artículo 0 valoraciones

Vol. 11 Núm.4. Julio-Agosto 2012 Pags. 574-575 Ann Hepatol 2012; 11(4)