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INTRODUCTION Currently, anticoagulation represents one of the most important strategies in the primary and secondary prevention of ischemic cerebrovascular disease (CVD). Cerebral embolism of cardiac origin is responsible for approximately 20% of all strokes. About half of all cases are due to non-valvular atrial fibrillation (NVAF), 40% to cardiac valvular disease and 30% to mural thrombi. In general, stroke patients with heart disease have a high risk of recurrence, thus requiring preventive anticoagulation. Other potential indications for the use of anticoagulants include strokes due to arterial dissection, antiphospholipid syndrome and cerebral venous thromboses. Furthermore, they have also been used in cases of recurrent stroke in spite of optimal dosages of antiplatelet agents.

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2013-07-24   |   425 visitas   |   1 valoraciones

Vol. 62 Núm.2. Marzo-Abril 2010 Pags. 141-151 Rev Invest Clin 2010; 62(2-ENGLISH)