Fragmento

Comment Transient elastogaphy (Fibroscan) is increasingly used in clinical practice for the non-invasive assessment of liver fibrosis, particularly in patients with chronic hepatitis C (CHC). When the technique was first described 10 years ago, the manufacturing company recommended criteria for reliable results, which included 10 valid measurements with a success rate of at least 60% and an interquartile range between median measurement values of less than 30%. Surprisingly, these criteria were met in only 21/40 transient elastography studies included in a metaanalysis. During the years, it also became apparent that liver stiffness is increased irrespective of fibrosis in a number of conditions, such as cholestasis, non-cirrhotic portal hypertension, liver congestion due to heart failure and necroinflammation. Further studies showing a correlation of liver stiffness with portal hypertension raised the question of potential transient increases in liver stiffness following meal ingestion, and this was indeed confirmed in a preliminary study.

Palabras clave:

2013-10-04   |   460 visitas   |   Evalua este artículo 0 valoraciones

Vol. 12 Núm.5. Septiembre-Octubre 2013 Pags. 839-810 Ann Hepatol 2013; 12(5)