Genomic and amino acid analysis of ompA gene of Chlamydia trachomatis serovar F from strains isolted in Mexico

Autores: Guerra Infante Fernando M, Basurto Tranquilino Marisol, de Haro Cruz María J., López Hurtado Marcela

Resumen

INTRODUCTION Chlamydia trachomatis is the most common cause of sexually transmitted bacterial infections. There are 19 recognized serovars of C. trachomatis, on the basis of major outer membrane protein (OmpA) composition (A-K and L1-L3).1 These serovars can be conveniently defined by sequence analysis and genotyping of the ompA gene. New genovariants of C. trachomatis have been discovered. For example, until late 2003 in Europe, a proctitis outbreak appeared (in men who have sex with men) whose etiologic agent was a genovariant of genotype L2 and which was identified as L2b. Later, other genovariants of L2 and L2b have been described in heterosexual women and men without signs or symptoms of lymphogranuloma venereum infection. Because of this, screening for nucleotide sequences of ompA gene of C. trachomatis from freshly isolated strains has intensified to identify the possible existence of new genovariants.

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2013-10-17   |   354 visitas   |   Evalua este artículo 0 valoraciones

Vol. 63 Núm.5. Septiembre-Octubre 2011 Pags. 544-546 Rev Invest Clin 2011; 63(5-ENGLISH)