Immunopathology of meningeal tuberculosis

Autores: Hernández Pando Rogelio, Soto Hernández José Luis, Salinas Lara Citlaltepetl

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CLINICAL CASE Woman, 35 years old from Mexico state, without any significant clinical antecedent for her disease which started on February 1996 with walking alterations, she was studied in a hospital from the north of Mexico (Tijuana city) where the diagnosis was spinal cord lesion which needed surgical treatment that the patient rejected. Six month after, the patient suffered cephalea, nausea and progressive deterioration of her mental functions, she was studied in the same hospital where the diagnosis of meningeal tuberculosis (TB) was established, antibiotic treatment was started and immediately was transferred to the Instituto Nacional de Neurocirugía in Mexico City, where she arrived with intense cephalea, fever, nausea, vomit, disorientation and recent memory lack, the clinical diagnosis was meningeal TB. The cerebral-spinal fluid (CSF) study reported glucose 12 mg/dL, proteins 161, cells 1,003. Magnetic resonance study showed several high density punctiform lesions in whole brain and in the cisternal system. The diagnosis was confirmed by isolation of M. tuberculosis from CSF. The patient left the hospital in general good conditions, with significant improvement of the muscular strength and normal CSF; she finished her antibiotics treatment and 10 years after manifested diverse sequels, such as cephalea, intermittent acufens and dizziness with neck pain and attention difficulty. The neurological exploration was normal.

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2013-11-05   |   603 visitas   |   Evalua este artículo 0 valoraciones

Vol. 65 Núm.4. Julio-Agosto 2013 Pags. 349-355 Rev Invest Clin 2013; 65(4-ENGLISH)